Like E. cloacae, Enterobacter aerogenes is gram-negative, facultative anaerobic rod, member of the family of the enterobacteriaciae.
Biochemical determination of Enterobacter aerogenes may be complicated by a slow reaction for motility and ornithine decarboxylase, resulting in a determination as Klebsiella pneumoniae or Raoultella planticola. The presence of an inducible class 1 betalactamase is can aid in a correct determination, since Klebsiella and Raoultella do not have a chromosomal AmpC betalactamase. Here a API 20E result for E. aerogenes:
Enterobacter infections are common and often affecting the urinary tract or present in clinical environments as a nosocomial or catheter related infection.
Enterobacter has a chromosomally encoded AmpC gene (Enterobacter are the E in the SPACE acronym). This inducible class 1 betalactamase makes E. aerogenes resistant to naturally resistant to amoxicillin, amoxicillin-clavulanate, narrow-spectrum, cephalosporins, and cefoxitin. Wild type strains are susceptible to carboxypenicillins and ureidopenicillins (pdf).
Antibiogram of a clinical isolate of E. aeroggenes:
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- Enterobacter cloacae
- AmpC betalactamase
- Serratia marcescens
- Enterobacteriaciae and betalactams
- Morganella morganii
- Hafnia alvei
- Klebsiella oxytoca
- Klebsiella pneumoniae
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