Meropenem has activity against:
- gram-positive bacteria
- Staphylococcus aureus
- Coagulase-negative staphylococci (methicillin susceptible)
- Streptococcus pyogenes
- Streptococcus agalactiae
- Streptococcus pneumoniae (PS)
- Streptococcus pneumoniae (PI)
- Streptococcus pneumoniae (PR)
- Viridans group streptococci
- Enterococcus faecalis
- Listeria monocytogenes
- Erysipelothrix ruhusiopathiae
- Corynebacterium spp (except C. jeikeium)
- Bacillus spp
- Peptostreptococcus spp
- Propionibacterium acnes
- Lactobacillus spp
- Clostridium difficile
- Clostridium perfringens
- Actinomyces spp
- gram-negative
- Escherichia coli
- Klebsiella pneumoniae
- Klebsiella oxytoca
- Proteus mirabilis
- Proteus vulgaris
- Enterobacter cloacae
- Enterobacter aerogenes
- Serratia marcescens
- Citrobacter freundii
- Citrobacter koseri
- Morganella morganii
- Salmonella spp
- Shigella spp
- Pseudomonas aeruginosa
- Acinetobacter spp
- Burkholderia cepacia
- Burkholderia pseudomallei
- Providencia rettgeri
- Haemophilus influenzae
- Moraxella catarrhalis
- Neisseria meningitides
Meropenem has no or insufficient activity against:
- gram-positive bacteria
- Enterococcus faecium
- Corynebacterium jeikeium
- gram-negative bacteria
- Stenotrophomonas maltophilia
- Acinetobacter baumannii (OXA and MBL phenotypes)
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