Proteus mirabilis is one of the three Proteus bacteria that is humanly pathogenic. Proteus spp are members of the enterobactericiae and a member of the Proteus-Providencia group and are oxidase-negative, catalase-positive, urease-positive (Salmonella are urease-negative) gram-negative rods, may be motile and ‘swarm’ on (blood and chocolate) agar plates:
Swarming of Proteus is inhibited when cultured on CLED agar.
A typical result for Api 20 E shows the biochemical properties for P. mirabilis:
- P. mirabilis is indole-negative.
- P. penneri is indole-negative
- P. vulgaris is indole-positive
P. mirabilis is a know pathogen of the urogenital tract (review). It’s capability to form biofilms on indwelling catheters complicates the long-term catheterisation of many patients.
Wild type Proteus mirabilis is resistant to nitrofurantoin (NI100) and colistin (CO150) but susceptible to betalactams including ampicillin, gentamicin, tobramycin, trimethoprim-sulfamethoxazole and meropenem:
Another typical Proteus mirabilis antibiogram showing resistance to ampicillin, nitrofurantoin, colisitin and in this case also trimethoprim-sulfamethoxazole:
A Proteus mirabilis antibiogram showing resistance to ampicillin, nitrofurantoin, colisitin and acquired resistance to trimethoprim-sulfamethoxazole and nalidixic acid:
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Related posts:
- Proteus vulgaris
- Proteus penneri
- Proteus-Providencia group
- Klebsiella pneumoniae
- Morganella morganii
- Serratia marcescens
- Klebsiella oxytoca
- Escherichia coli
- Pseudomonas aeruginosa
- Yersinia
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